Welcome to the Maia Lab
We are interested in functional genomics, genetic regulation and cancer. We study allelic imbalance in gene expression, a common feature of our genome. This unequal expression can contribute to susceptibility to common diseases. Our main aim is to try to use this concept to develop new methods to study predisposition to breast cancer. Additionally, we are investigating the role that this imbalance can play in tumour biology, namely in the effect of mutations and treatment response.
Where We Are
We are members of the CBMR (Centre for Biomedical Research). We are part of the Regenerative Medicine Programme at the Department of Biomedical Sciences and Medicine at the University of Algarve (UAlg).
Our lab is located on the ground floor of the Building 8 in the Gambelas Campus of UAlg.
We are also 5 min away from the beach!
Selected Maia AT#, Antoniou AC, O’Reilly M, Samarajiwa S, Dunning M, Kartsonaki C, Chin SF, Curtis CN, McGuffog L, Domchek SM, EMBRACE, Easton DF, Peock S, Frost D, Evans DG, Eeles R, Izatt L, Adlard J, Eccles D, GEMO Study
Cis-regulatory variants in susceptibility to breast cancer We are using our knowledge of cis-regulation in normal breast tissue to prioritise GWAS loci for functional characterisation. This approach will speed up the unveiling of the biological mechanisms at the basis of
Project Grants Current 2018-2021 Foundation for Science and Technology, Portugal, Project Grant; “Decoding breast cancer evolution through mutant allele differential expression signatures” AAC n.º 02/SAICT/2017
What they say about us…
Even for a short-term experience I could find a very complete environment where all members of the lab have the best qualifications to improve your critical thinking in such a stimulant and provocative way, and work for the purpose of doing good science.